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GenScript corporation
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GenScript corporation
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GenScript corporation
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GENBODY Inc
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GENBODY Inc
svnt rapid kit ![]() Svnt Rapid Kit, supplied by GENBODY Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/result/svnt rapid kit/product/GENBODY Inc Average 90 stars, based on 1 article reviews
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Image Search Results
Journal: Nature
Article Title: Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants
doi: 10.1038/s41586-021-03676-z
Figure Lengend Snippet: a , Table indicating (1) the total number of unique nanobody genes identified from llama and three nanomice phage display libraries following selection for RBD binding; (2) the number of nanobodies enriched at least tenfold after selection; (3) the number of nanobodies with a unique CRD3; and (4) the different clusters of nanobodies that share similar CDR3 s (with no more than 2 amino acid differences). b , Table showing in vitro neutralization results for the six leading nanobodies using the sVNT kit of GenScript. c , Dot plot depicting the extent of enrichment ( y axis) and frequency ( x axis) of unique nanobodies after RBD selection of llama (left) or nanomouse 1 (right) libraries. Green circles represent nanobodies that block ACE2–RBD interactions in vitro, black circles are nanobodies that do not efficiently block ACE2–RBD interactions, and grey dots represent untested nanobodies. d , Top graph shows protein alignment of the six nanobodies isolated from llama and nanomice immunized with SARS-CoV-2 spike and RBD. Bottom table shows detailed information of the VHH, D and J domains of nanomouse nanobodies. e , Table depicting equilibrium ( K D ), association ( K on ) and dissociation ( K off ) constants obtained for each nanobody as a monomer (black) or trimer (red) form.
Article Snippet: Extended Data Fig. 5 Isolation of anti-SARS-CoV-2 RBD nanobodies. a , Table indicating (1) the total number of unique nanobody genes identified from llama and three nanomice phage display libraries following selection for RBD binding; (2) the number of nanobodies enriched at least tenfold after selection; (3) the number of nanobodies with a unique CRD3; and (4) the different clusters of nanobodies that share similar CDR3 s (with no more than 2 amino acid differences). b , Table showing in vitro neutralization results for the six leading nanobodies using the
Techniques: Selection, Binding Assay, In Vitro, Neutralization, Blocking Assay, Isolation